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李楠

 

李楠,女,1989年生于陜西西安,理學博士,副教授,碩士生導師。2011年畢業于西北大學,獲理學學士學位;2016年畢業于中國科學院化學研究所,獲理學博士學位。歷任中國農業科學院農業質量標準與檢測技術研究所助理研究員、副研究員。現任教于新材料與化工學院制藥工程系。長期致力于復雜樣品中藥物及其代謝物檢測新材料與新技術研發。先后主持承擔國家自然科學基金面上項目、青年項目,國家重點研發計劃項目子課題等10余項,榮獲神農中華農業科技獎、全國農牧漁業豐收獎、中國農業科學院科學技術成果獎、中國分析測試協會科學技術獎等一等獎4項,以第一/通訊作者身份在Journal of Hazardous Materials, Analytical Chemistry, ACS applied materials & interfaces, Talanta, Journal of chromatography A等期刊發表SCI論文13篇,累計影響因子50以上,申請國家發明專利11項,其中6項已授權。

I. 主要研究工作

1.  生物醫藥快速檢測技術研發;

2.  生物醫藥分離富集材料研發;

3.  未知有機有害物質化學結構鑒定及標準物質合成。

II. 學術獎勵

1.  全國農牧漁業豐收獎“畜禽產品重點危害因子快速精準檢測關鍵技術及應用”,一等獎,2019-2021.

2.  神農中華農業科技獎“農產品中主要危害因子高效識別與風險評估關鍵技術及應用”,一等獎,2020-2021.

3.  中國農業科學院科學技術成果獎“主要農產品風險因子識別與安全評價關鍵技術研發及應用”,一等獎,2020.

 4.  中國分析測試協會科學技術獎“構建聚合物分子溫度劑及其細胞成像應用研究”,一等獎,2016.

III. 主持承擔項目

1.  國家自然科學基金面上項目:富硫蔬菜中氯代苯類農藥新型含硫代謝物形成機制及風險評估(項目號:32372445),項目負責人,2024-2027.

2.  國家自然科學青年基金項目:識別氨基糖苷類抗生素的比率型熒光印跡陣列傳感基礎研究(項目號:21804138),項目負責人,2019-2021.

3.  國家重點研發計劃項目子課題:畜禽類地理標志產品特色風味品質挖掘及指紋構建(項目號:2022YFF0606801),項目負責人,2022-2026.

4.  農業農村部財政項目:果蔬產品中新型代謝物巰基百菌清殘留風險評估(項目號:2022110043007955),項目負責人,2022.

IV. 代表性學術論文

1.  Yilin Cao, Nan Li*, Yun Li, Jing Qiu, Haixia Sui, Daoyuan Yang, Yongzhong Qian*. Sulfhydrylation of chlorothalonil in the pak choi from the cultivation to sample analysis and the exposure risk assessment. Journal of Hazardous Materials, 2025, 485, 136920.

 2. Nan Li, Yining Xia, Yun Li, Qi Jia, Jing Qiu*, Yanyang Xu, Zian Wang, Zhe Liu, Yongzhong Qian*. Untargeted screening, quantitative analysis, and toxicity estimation of degradation products of fluazinam in vegetables. Microchemical Journal, 2023, 190, 108584.

3. Nan Li, Yining Xia, Yanyang Xu, Yun Li, Qi Jia, Jing Qiu*, Yongzhong Qian*, Zian Wang. Identification and analysis of the degradation products of chlorothalonil in vegetables. Journal of Chromatography A, 2022, 1686, 463647.

4.  Nan Li, Jing Qiu*, Yongzhong Qian. Polyethyleneimine-modified magnetic carbon nanotubes as solid-phase extraction adsorbent for the analysis of multi-class mycotoxins in milk via liquid chromatography-tandem mass spectrometry. Journal of Separation Science, 2021, 44, 636-644.

5.  Nan Li, Jing Qiu*, Yongzhong Qian. Amphiphilic block copolymer-grafted magnetic multi-walled     carbon nanotubes as QuEChERS    adsorbent for simultaneous determination of mycotoxins and pesticides in grains via liquid chromatography tandem mass spectrometry. Microchimica Acta, 2020, 187, 648.

6. Huiying Liu, Nan Li*, Xubo Liu, Yongzhong Qian, Jing Qiu, Xiaoning Wang. Poly(N-acryloyl-glucosamine-co-methylenebisacrylamide)-based hydrophilic magnetic nanoparticles for the extraction of aminoglycosides in meat samples. Journal of Chromatography A, 2020, 1609, 460517.

7.  Nan Li, Jing Qiu*, Huiying Liu, Zhijun Chen, Yongzhong Qian. Thermoregulated extraction of luteolin under neutral conditions using oligo(ethyleneglycol)-based magnetic nanoparticles with Wulff-type boronate affinity. Journal of Chromatography A, 2019, 1607, 460396.

8. Nan Li, Yue Song, Jing Qiu*, Yuechen Zhao, Yongzhong Qian. Polymer brushes-containing coordination polymer networks on monolith for rapid solid phase extraction of multi-class drug residues in meat samples. Talanta, 2018, 185, 573-580.

9. Nan Li, Li Qi*, Juan Qiao, Yi Chen. Ratiometric and selective protein detection based on dissociation of aqueous polymer-pyrene/g-cyclodextrin inclusion complex. Analytical Chemistry, 2016, 88: 1821-1826.

10. Nan Li, Ying Shen, Li Qi *; Zhibo Li, Juan Qiao, Yi Chen. Preparation of an amino acid-based polymer monolith for trimodal liquid chromatography. RSC Advances, 2015, 5, 61436.

11. Nan Li, Li Qi*, Ying Shen, Juan Qiao, Yi Chen. Novel oligo(ethylene glycol)-based molecularly imprinted magnetic nanoparticles for thermally modulated capture and release of lysozyme. ACS Applied Material &Interfaces, 2014, 6, 17289-17295.

12. Nan Li, Wei Zheng, Ying Shen, Li Qi*, Yaping Li, Juan Qiao, Fuying Wang, Yi Chen*. Preparation of a novel polymer monolith with functional polymer brushes by two-step atom transfer radical polymerization for trypsin immobilization. Journal of Separation Science, 2014, 37, 3411-3417.

13. Nan Li, Li Qi*, Ying Shen, Yaping Li, Yi Chen. Thermoresponsive oligo(ethylene glycol)-based polymer brushes on polymer monoliths for all-aqueous chromatography. ACS Applied Material &Interfaces, 2013, 5, 12441-12448.

14.  Nan Li, Li Qi *, Ying Shen, Yaping Li, Yi Chen. Amphiphilic block copolymer modified magnetic nanoparticles for microwave-assisted extraction of polycyclic aromatic hydrocarbons in environmental water. Journal of Chromatography A, 2013, 1316, 1-7.

V. 發明專利

1.李楠,陳潮文,邱靜,錢永忠,劉會影.一種聚苯乙烯-二乙烯基苯修飾的磁性納米管復合材料及其應用.中華人民共和國發明專利,ZL202011425936.0,授權公告日:2020.12.08.

2.李楠,邱靜,錢永忠.一種溫敏 Wulff 型硼親和納米顆粒及其制備方法與用途. 中華人民共和國發明專利,ZL201910300674.6,授權公告日:2019.04.15.

3.李楠,李耘,邱靜,錢永忠.一種聚乙烯亞胺功能化嵌段聚合物磁性納米顆粒復合材料及其制備方法和應用.中華人民共和國發明專利,ZL201911383003.7,授權公告日:2019.12.27.

4.李楠,李耘,邱靜,錢永忠.一種生物胺配位印跡材料、生物胺熒光陣列傳感器及其制備方法和用途.中華人民共和國發明專利,ZL201911382993.2,授權公告日:2019.12.27.

5.李楠,邱靜,錢永忠.基于聚單糖的溫度響應型氨基糖苷類抗生素印跡磁性納米顆粒及其制備方法和應用.中華人民共和國發明專利,ZL201811530175.8,授權公告日:2018.12.14.

6.李楠,邱靜,錢永忠,宋月.聚合物整體柱、基于所述整體柱的固相萃取過濾器及其制備方法和用途.中華人民共和國發明專利,ZL201710117790.5,授權公告日:2017.03.01.

VI. 招生信息

本人主要招收生物與醫藥類(0860)專業學位碩士(制藥工程領域086002)。誠摯歡迎化學高分子材料分析化學等相關專業熱愛科研刻苦認真的同學加入本團隊。